Patients reported their decision quality and physician visit satisfaction using validated surveys. A novel decision aid was used in both encounters to disclose the CHD risk estimates and facilitate SDM regarding statin use. A genetic counselor disclosed this information followed by a physician visit for SDM regarding statin therapy. We randomized 207 patients, age 45-65†years, at intermediate CHD risk, and not on statins, to receive the 10-year risk of CHD based on conventional risk factors alone (n=103) or in combination with a genetic risk score (n=104). N2 - Whether disclosure of genetic risk for coronary heart disease (CHD) influences shared decision-making (SDM) regarding use of statins to reduce CHD risk is unknown. Data management was performed with the use of REDCap, which is funded by the Center for Clinical and Translational Science (UL1TR000135).Ĭopyright © 2017 American Federation for Medical Research. This study was funded as part of the National Human Genome Research Institute-supported eMERGE (Electronic Records and Genomics) Network (U01HG04599 and U01HG006379) and the Mayo Clinic Center for Individualized Medicine.
Kullo iftikhar mayo clinic trial#
T2 - Results from a randomized clinical trial T1 - Shared decision-making following disclosure of coronary heart disease genetic risk Disclosure of CHD genetic risk using an electronic health record-linked decision aid did not adversely affect SDM or patients' satisfaction with the clinical encounter.", Quantitative analyses of a random subset of 80 video-recorded encounters using the OPTION5 scale also showed no significant difference in SDM between the two groups.
There were no statistically significant differences between the two groups in the SDM score, satisfaction with the clinical encounter, perception of the quality of the discussion or of participation in decision-making and physician visit satisfaction scores. We randomized 207 patients, age 45-65€ years, at intermediate CHD risk, and not on statins, to receive the 10-year risk of CHD based on conventional risk factors alone (n=103) or in combination with a genetic risk score (n=104). Disclosure of CHD genetic risk using an electronic health record-linked decision aid did not adversely affect SDM or patients' satisfaction with the clinical encounter.Ībstract = "Whether disclosure of genetic risk for coronary heart disease (CHD) influences shared decision-making (SDM) regarding use of statins to reduce CHD risk is unknown.
Whether disclosure of genetic risk for coronary heart disease (CHD) influences shared decision-making (SDM) regarding use of statins to reduce CHD risk is unknown.
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